Center for Research in Oral Cancer

Faculty of Dental Sciences

Center for Research in Oral Cancer

University of Peradeniya

Research Publications

  • Bazarsad S, Zhang X, Kim KY, Illeperuma R, Jayasinghe RD, Tilakaratne WM, Kim J. Identification of a combined biomarker for malignant transformation in oral submucous fibrosis. J Oral Pathol Med. 2016 Aug 6. doi: 10.1111/jop.12483. [Epub ahead of print]

  • RP Ekanayaka, WM Tilakaratne. Oral submucous fibrosis : Review on mechanisms of malignant transformation. Oral Surg, Oral Med, Oral Pathol, Oral Radiol 2016;122 (2),192–199. doi.org/10.1016//j.oooo.2015.12.018

  • L.A.H. Jayasinghe, P.M. Peiris, WM Tilakaratne, A.M. Attygalla, R.D. Jayasinghe, M.A.M. Sitheeque, B.S.M.S. Siriwardena. Clinically malignant exophytic lesions in the background of oral submucous fibrosis: report of 5 cases. 2016;122 (2),210–215. DOI: http://dx.doi.org/10.1016/j.oooo.2016.06.001

  • WM Tilakaratne, Rasika Priyadharshani Ekanayaka, Saman Warnakulasuriya Oral submucous fibrosis: A historical perspective and a review on aetiology and pathogenesis. Oral Surg, Oral Med, Oral Pathol, Oral Radiol August 2016;122, (2),178–191. doi.org/10.1016/j.oooo.2016.04.003.

  • RP Ekanayaka, MPB Herath, RD Jayasinghe, MAM Sitheeque, H Amarasinghe, WM Tilakaratne. Intralesional corticosteroids as a treatment for restricted mouth opening in oral submucous fibrosis. Oral Surg, Oral Med, Oral Pathol, Oral Radiol 2016;122, (2) 224–231. doi.org/10.1016/j.oooo.2015.11.023

  • Siriwardena BSMS, Jayathilake DSY, Pitakotuwage TN, Illeperuma RP, Kumarasiri PVR3, Attygalla AM, Peiris HRD, Tilakaratne WM. Demographic and Histopathological Differences of Oral squamous Cell Carcinoma; Analysis of 4394 Cases from Sri Lanka. J Clin Exp Oncol 2015; 4:4

  • PGCL Nanayakkara, WL Dissanayaka, BG Nanayakkara, EAPD Amaratunga, WM Tilakaratne. Comparison of spatula and cytobrush cytological techniques in early detection of oral malignant and premalignant lesions: a prospective and blinded study. 2016 Apr;45(4):268-74. doi: 10.1111/jop.12357

  • Siriwardena BSMS. ,Takaaki Tsunematsu, Guangying Qi, Naozumi Ishimaru et alInvasion-Related Factors as Potential Diagnostic and Therapeutic Targets in Oral Squamous Cell Carcinoma—A Review. International Journal of Molecular Sciences 19 (5), 1462-82

  • RK De Silva, B Siriwardena, A Samaranayaka, W Abeyasinghe et al. A model to predict nodal metastasis in patients with oral squamous cell carcinoma. PloS one 13 (8), e0201755

  • B. S. M. S. Siriwardena, K. L. T. D. Jayawardena, N. H. Senarath, W. M et al. An Evaluation of Clinical and Histopathological Aspects of Patients with Oral Submucous Fibrosis in the Background of Oral Squamous Cell Carcinoma. BioMed Research International 2018 (1), 7

  • Siriwardena BSMS Rambukewela IK, PitakotuwageTN, Udagama MNGPK, Kumarasiri . A Predictive Model to Determine the Pattern of Nodal Metastasis in Oral Squamous Cell Carcinoma. BioMed Research International 2018 (1), 1-7

  • LAH Jayasinghe, PM Peiris, WM Tilakaratne, AM Attygalla, RD Jayasinghe, MAM Sitheeque, BSMS Siriwardena*.Clinically malignant exophytic lesions in the background of oral submucous fibrosis: report of five cases. Oral Surg Oral Med Oral Path Oral Radiol Vol 122,(2), 2016. doi:10.1016/j.oooo.2016.06.001

  • Siriwardena BSMS, Jayathilake DSY, Pitakotuwage TN, Illeperuma RP, Kumarasiri PVR, Attygalla AM, Peiris HRD, Tilakaratne WM. Demographic and Histopathological Differences of Oral Squamous Cell Carcinoma; Analysis of 4394 Cases from Sri Lanka.J Clin Exp Oncol 2015, 4:4 http://dx.doi.org/10.4172/2324-9110.1000149.

  • RMAR Rajapakshe, RW Pallegama, PR Jayasooriya, BSMS Siriwardena, DK Dias, AM Attygalla, S Hewapathirana, JU Weerasinghe, WM Tilakaratne. A Retrospective analysis to determine factors contributing to the survival of patients with oral squamous cell carcinoma. Cancer Epidemiology. DOI: http://dx.doi.org/10.1016/j.canep.2015.02.011

  • BSMS Siriwardena, RMSGK Rasnayaka, Y Masood. M. Masood. PVR Kumarasiri, WM Tilakaratne. Predictive model of oral cancer metastasis for different cancer sites and age groups. Journal of investigative and clinical dentistry, (2015),6 , 1–5

  • Siriwardena B. S. M. S, Jayasinghe RD, Ratnatunga N, Tilakaratne WM. Solitary mastocytoma: A rare presentation on the buccal mucosa. Case Reports in Clinical Medicine, 2, 174-175. doi: 10.4236/crcm. 2013.23062.

  • Siriwardena B. S. M. S , Jayasooriya P. R Palitha Ratnayake, WM Tilakaratne Metastatic tumours of the oral and maxillofacial region:A retrospective analysis of 18 cases. Merit Research Journal of Biochemistry and Bioinformatics Vol. 1(1) pp. 001-004, May, 2013

  • Medawala SH, DL Ratnayake, PR Jayasooriya, B Siriwardene, WM Tilakaratne,Malignant transformation of Oral Lichen Planus: The first two cases reported in Sri Lanka and literature review ... Sri Lanka Dental Journal 2017; 47(01) 29-37 47 (1), 29-37

  • ALM Rizan, Ruwan Jayasinghe, BSMS Siriwardena. Attygalla AM. An analysis of cervical lymph node metastasis in oral squamous cell carcinoma - relationship among clinical, ultrasonographical and histopathological status of nodal metastasis. Sri Lanka Dental Journal 45 (02), 75-82

  • BSMS Siriwardena, A Tilakaratne, WM Tilakaratne. A Comparative Study of Oral Squamous Cell Carcinoma in the Young and the Old in Sri Lanka. Sri Lanka Dental Journal 45 (02), 69-73
  • Illeperuma RP, Bandara WMKM, Do KK, Jayasinghe RD, Siriwardene BSMS, Jin K, Tilakeratne WM. Antioxidant rich tropical herbs to combat AN induced OPMDs. In: proceeding of the 72nd AAOMP conference; 2018 June 23-28; Vancouver, Vancouver: AAOMP; 2018. (Page 181)

  • Bandara WMKM, Do KK, Jayasinghe RD, Siriwardene BSMS, Tilakeratne WM, Jin K, Illeperuma RP. EXPRESSION OF ɤ–H2AX AND P53 IN ORAL CANCER AND ORAL POTENTIAL MALIGNANT DISORDERS WITH ARECA NUT HISTORY. In: proceeding of the Perdeniya University International Research Sessions; 2016 Nov 4-5; Kandy, Peradeniya: iPURSE; 2016. Abstract nr 414 (Oral Presentation)

  • Bandara WMKM, Illeperuma RP, Do KK, Jayasinghe RD, Siriwardene BSMS, Tilakeratne WM, Jin K. Areca-Nut Induced DNA Damage Can Be Reversed By Shumacheriacastaneifolia. In: proceeding of the 18th IAOP – XXV IAOMP conference; 2016 Sep 8-11; Chennai, Chennai: IAOP; 2016. Abstract nr 199 (Oral Presentation)

  • Bandara WMKM, Illeperuma RP, Do KK, Jayasinghe RD, Siriwardene BSMS, Tilakeratne WM, Jin K. TESTING EFFICACY OF ANTIOXIDANT RICH HERBAL EXTRACT IN REDUCING ARECA NUT INDUCED CARCINOGENISIS. In: proceeding of the 129th Anniversary International Medical Congress Sri Lanka Medical Association; 2016 July 27; Colombo: SLMA; 2016. Abstract nr 296 (Oral Presentation)

  • Bandara WMKM, Fujiwara N. EFFECTS OF ACUTE HIGH GLUCOSE AND OSMOLALITY ON CHANGES OF INTRACELLULAR CALCIUM LEVEL IN MOUSE NEOCORTICAL SLICES. In: proceeding of the Perdeniya University International Research Sessions; 2015 Nov 5-6; Kandy, Peradeniya: iPURSE; 2015. Abstract nr 574 (Oral Presentation)

  • Bandara WMKM, Illeperuma RP, Do KK, Jayasinghe RD, SiriwardeneBSMS, Tilakeratne WM, Jin K. ANALYSIS OF DNA DOUBLE STRAND DAMAGE DURING ORAL CARCINOGENISIS IN ARECA NUT CHEWERS. In: proceeding of the International Symposium for Oral Cancer and Precancer; 2015 Oct 01; Seoul, Seodaemun-gu: ISOP; 2015. Abstract nr 10(Oral Presentation)
  • Karunatilaka HDNU, Siriwardena BSMS, Tilakeratne WM. ANALYSIS OF THE SIGNIFICANCE OF PATTERN OF INVASION IN RELATION TO PROGNOSIS OF ORAL AQOUMOUS CELL CARCINOMA. In: proceeding of the Perdeniya University International Research Sessions; 2015 Nov 5-6; Kandy, Peradeniya: iPURSE; 2015. Abstract nr 548 (Poster Presentation)

  • Karunatilaka HDNU, Siriwardena BSMS, Tilakeratne WM. HISTOLOGICAL PARAMETERS AND EXPRESSION OF EGFR AND β-CATENIN IN ORAL SQOUMOUS CELL CARCINOMA; A PRELIMANARY STUDY. In: proceeding of the Perdeniya University International Research Sessions; 2016 Nov 4-5; Kandy, Peradeniya: iPURSE; 2016. Abstract nr 535 (Oral Presentation)